Through the Kreb’s cycle and glycolysis, NAD+ accepts a hydrogen ion to form NADH during ATP production. NADH then donates electrons during oxidative phosphorylation in the electron transport chain to further generate ATP. It is this balance of redox reactions that controls the NAD+ to NADH ratio and this ratio is crucial for homeostasis, generation of oxidative stress, antioxidation, and cell survival or death. If NAD+ and ultimately ATP production in our body is less than optimal, a whole list of body processes will be affected and this contributes to the overall perception of “fatigue”.
NAD+
Natural Solutions For A Healthy + Beautiful Mind, Body + Life
NAD+ Therapy — Cellular Energy, Anti‑Aging & Total Wellness
Unlock Your Body’s Cellular Power
NAD+ (Nicotinamide Adenine Dinucleotide) has rapidly emerged in the wellness, longevity, and anti‑aging world as a foundational molecule that supports cellular energy production, metabolism, brain health, and healthy aging. At Body Blu, our therapy — available as customized injections and IV infusions — is designed to help restore your body’s optimal levels and support overall vitality, cognitive clarity, metabolism, and resilience.
As we age, NAD+ naturally declines, which can negatively affect energy, mitochondrial function, and cellular repair processes. Restoring levels with professional medical therapy can help your cells function better, your mind feel sharper, and your body more vital.
Boosting levels has been shown to support metabolism, DNA repair, and cellular health. According to research on NAD+ metabolism and its roles in cellular processes and aging, restoring levels may help slow age-related cellular decline.
What is NAD+ and Why It Matters
NAD+ is a coenzyme found in every living cell that plays a central role in converting nutrients into usable energy (ATP) inside mitochondria — the “powerhouses” of the cell. It is essential for fundamental biological processes, including:
Energy metabolism and ATP production
DNA repair and genomic stability
Cellular signaling and stress response
Neurological function and cognition
Levels are highest early in life and decline significantly with age, stress, lifestyle, and environmental factors. This decline correlates with reduced cellular energy, slower repair mechanisms, and increased oxidative stress — all hallmarks of aging.
Why Consider NAD+ Therapy
When NAD+ levels drop, many systems in the body become less efficient. That can show up as fatigue, reduced mental clarity, slower metabolism, mood changes, and even visible signs of aging.
Restoring levels has become a priority for people who want to feel more energized, think more clearly, and support metabolic health. Clinical studies and wellness research highlight multiple potential benefits of boosting levels in the body, especially when paired with a healthy lifestyle.
Here’s how our therapy can support your health:
1. Boosted Cellular Energy & Metabolism
NAD+ is central to the metabolic pathways that convert food into energy. By enhancing mitochondrial efficiency and supporting key metabolic enzymes, higher levels help your cells produce more energy with greater efficiency. That can translate to:
Increased daily energy levels
Reduced fatigue and afternoon crashes
Better endurance and physical performance
As NAD+ plays a role in fat and glucose metabolism, it also supports metabolic flexibility, helping your body switch smarter between fuels like fats and carbohydrates throughout the day.
2. Cognitive Clarity & Brain Health
Your brain relies on energy. When NAD+ levels drop, neurons have less fuel, and cognitive processes like memory, focus, and decision‑making can feel slower or foggy.
Emerging research suggests that maintaining healthy levels may:
Enhance clarity, focus, and mental sharpness
Support brain cell communication
Reduce cognitive fatigue
Although studies are ongoing, early results show that NAD+ can help support long‑term neurological health and cognitive resilience.
3. Anti‑Aging Support at the Cellular Level
One of the most discussed aspects of NAD+ is its connection to healthy aging. Cellular aging is influenced by oxidative stress, DNA damage, and loss of metabolic efficiency — all areas where it plays a key role. By supporting DNA repair enzymes and mitochondrial function, our therapy helps:
Reduce oxidative damage
Support cell repair and survival pathways
Maintain youthful cellular function
Although NAD+ isn’t a “fountain of youth,” it helps your body’s natural systems work better over time.
4. Mood Regulation & Resilience
Many people report noticeable improvements in mood, stress response, and emotional stability after therapy. This is likely due to NAD+’s influence on neurological signaling and energy metabolism in brain cells. Early clinical observations and patient experiences suggest that therapy may help:
Enhance stress resilience
Improve emotional balance
Support neurotransmitter function
Be sure to consult your healthcare provider before beginning therapy, especially if you have existing mood or neurological conditions.
5. Metabolic Health & Weight Management
NAD+ supports key metabolic regulators — including enzymes that influence glucose uptake, insulin sensitivity, and fat oxidation. Research has shown that increased levels can help improve metabolic health markers, such as:
Improved insulin sensitivity
Better fat utilization during activity
More efficient energy production
Stable blood sugar levels
While NAD+ therapy isn’t a standalone weight‑loss solution, it can be a powerful component of a broader metabolic health plan.
NAD+ Therapy Options at Body Blu
Intramuscular NAD+ Injections
Quick, convenient injections
Custom dosing based on your individual needs
Excellent option for ongoing wellness, mental clarity, and energy
IV Infusions for High‑Dose Therapy
Higher bioavailability for deep support
Enhanced delivery to tissues throughout the body
Ideal for those seeking advanced metabolic, energy, or anti‑aging support
Body Blu offers a range of dosing options, from introductory therapy to advanced high‑dose IV treatments tailored to your goals.
NAD+ FAQ:
What to expect at your first treatment:
Your initial session at Body Blu will include:
Focused medical evaluation with our providers
Customized dosing plan based on your health goals
Safe administration by trained medical professionals
Observation period to monitor your response
The injection process is similar to a B12 shot, however your first visit will take approximately 20-25 minutes as you will be asked to stay 10-15 minutes after the injection.
The benefits are dose dependent, meaning that improvements can be more noticeable and longer-lasting as greater dosages are introduced into the body. At Body Blu, we offer varying dosages intramuscularly, and high dose NAD+ is available through IV administration.
Can there be side-effects?
NAD+ therapy is generally well tolerated, but as with any medical treatment, individual responses can vary. Some people may experience mild side effects such as:
Temporary nausea
Head Pressure
Flushing
Increased heart rate
These are usually short‑lived and monitored during your visit. At Body Blu, we start with controlled doses to minimize discomfort and ensure your safety throughout the process.
It’s also important to consult your healthcare provider before therapy, especially if you are pregnant, breastfeeding, have a chronic health condition, or are taking medications.
Side effects most often occur from dosing too rapidly. At Body Blu we make a point to introduce NAD+ gradually to avoid any uncomfortable side effects. If these side effects occur, they are generally short-lasting and can be monitored in the short time that you are with your doctor at Body Blu.
How does NAD+ work at the cellular level?
Do NAD+ levels really decline with age?
Yes — levels naturally decrease over time, which can impact energy, metabolism, and cellular repair functions.
How soon will I notice results?
Some individuals feel improved energy or clarity within days, while others may see gradual changes over a few weeks of consistent therapy.
Can NAD+ help with aging?
NAD+ supports cellular mechanisms tied to aging processes, though it is part of a holistic approach to healthy aging rather than a singular cure.
Start Your Anti-Aging Journey Today
Ready to support your cellular energy, cognitive focus, and metabolic health? Body Blu’s NAD+ therapy combines medical expertise with personalized wellness strategies to help you look, feel, and perform your best.
📍 Book your NAD+ consultation & therapy session today — choose from our locations in California and start feeling the difference of optimized cellular function.
Where would you like to book your Appointment?
The Little Italy Downtown San Diego location does not take appointments, and is a walk-in only location. Click here for more information on the Little Italy location.
Meet Our Medical Team
Our Professional And Highly Trained Doctors

Meet Jordan Scott, ND
You will find Dr. Scott at the Mission Valley and Little Italy locations. Her experience is varied ranging from treating patients with cardiovascular disease, recovery from drug and alcohol abuse, hormone imbalance, weight loss, and musculoskeletal pain, among other primary care conditions.

Meet Joseph Scarpuzzi, ND
You will find Dr. Scarpuzzi at the Cardiff and Temecula locations. He provides natural therapies for men and women looking for hormone treatments, gut health, natural aesthetic procedures, and nutritional therapies. He’s dedicated to finding the root cause and helping his patients achieve optimal health.
Results may very person to person. Services, prices + availability are subject to change without prior notice. Please call ahead for verification. Body Blu does not bill insurance. We accept cash + credit cards only. We do not accept personal checks. Patients, please contact your insurance carrier to pre-authorize use of FSA + HSA cards for allowable treatments. Payment is due before or upon receipt of services. We do not offer refunds for services, treatments + pre-paid packages. Please review our Practice Policies for detailed information.